An ETF that invest in Immunotherapy

An ETF that invest in ImmunotherapyAn ETF that invest in Immunotherapy

Loncar Cancer Immunotherapy ETF (CNCR), An ETF that invest in Immunotherapy

ABOUT THE FUND

The Loncar Cancer Immunotherapy ETF, An ETF that invest in Immunotherapy, seeks to track the LCINDX index. It is made up of a basket of companies that develop therapies to treat cancer by harnessing the body’s own immune system. Immunotherapy is a transformational field within the biotechnology space that is expected to become the foundational treatment for cancer over the next ten years. A sector ETF focusing on a unique technology like cancer immunotherapy allows investors to focus on interest areas more precisely than broad indices. LCINDX is an equal-weighted index containing both large pharmaceutical and growth-oriented biotechnology companies that are leading in this approach.

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INVESTMENT RATIONALE

Cancer immunotherapy has become an important sector in the biotechnology space and is changing the way many cancers are treated. While traditional medicines like chemotherapies often give cancer a broad punch, the benefit of using immunotherapy is derived from the immune system’s dynamic nature and the way it can more precisely be tailored to fight a patient’s disease. Some immunotherapies have exhibited uncommon results in clinical trials.

Today, many new classes of cancer immunotherapies are being developed. These include checkpoint inhibitors (which are already FDA approved for melanoma and lung cancer), cancer vaccines, bispecific antibodies, and chimeric antigen receptor (CAR-T) technologies. With this distinct sector focus, the fund aims to help investors capture a growth area of the biotechnology space. At the same time, it will support this method of treating cancer by providing capital to public companies that are leaders in the space.

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* Fund holdings and allocations are subject to change at any time and should not be interpreted as an offer of these securites.

INDEX PROVIDER

Loncar Investments LLC was founded by noted independent biotech investor and analyst Brad Loncar. Mr. Loncar regularly provides his unique insight and analysis on this market segment to the investment community via a variety of publishing platforms. Through Loncar Investments LLC, Mr. Loncar incorporates his extensive research into biotech companies and technologies to develop indexes focused on precise investment opportunities.

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Disclaimer

The Fund’s investment objectives, risks, charges and expenses must be considered carefully before investing. The summary and statutory prospectuses contain this and other important information about the investment company, and it may be obtained by calling 800-617-0004. Read it carefully before investing. Investing involves risk, including the possible loss of principal. Shares of any ETF are bought and sold at market price (not NAV), may trade at a discount or premium to NAV and are not individually redeemed from the Fund. Brokerage commissions will reduce returns. The Fund will invest in immunotherapy companies which are highly dependent on the development, procurement and marketing of drugs and the protection and exploitation of intellectual property rights. A company’s valuation can also be greatly affected if one of its products is proven or alleged to be unsafe, ineffective or unprofitable. The costs associated with developing new drugs can be significant, and the results are unpredictable. The process for obtaining regulatory approval by the U.S. Food and Drug Administration or other governmental regulatory authorities is long and costly and there can be no assurance that the necessary approvals with be obtained and maintained.

The Fund may invest in foreign securities, which involve political, economic, currency risk, greater volatility, and differences in accounting methods. The Fund is non-diversified meaning it may concentrate its assets in fewer individual holdings than a diversified fund. Therefore, the Fund is more exposed to individual stock volatility than a diversified fund. The Fund invests in smaller companies, which may have more limited liquidity and greater volatility compared to larger companies. The Fund is not actively managed and may be affected by a general decline in market segments related to the index. The fund invests in securities included in, or representative of securities included in, the index, regardless of their investment merits. The performance of the fund may diverge from that of the Index and may experience tracking error to a greater extent than a fund that seeks to replicate an index.

The Loncar Cancer Immunotherapy ETF, An ETF that invest in Immunotherapy, is distributed by Quasar Distributors, LLC. Loncar Investments is the index provider of the Fund. INDXX, LLC helps Loncar with risk management and index construction.

Utveckling olika investeringar (1-5 mars)

Utveckling olika investeringar (1-5 mars)

Utveckling olika investeringar (1-5 mars) Veckan som gick. Veckan avslutades med ett rally. Dow Jones avslutade veckan med en uppgång på 2,3% och S&P gick upp med 3,1% och Nasdaq gick upp med 3,9%.

Utvecklingen i Europa och Asien var också positiv. Den europeiska marknaden gick upp med 5% och i Asien stannade utvecklingen kring 4%. Latinamerika gick upp med cirka 5%. Bäst utveckling hade Sydafrika med en utveckling på 8,2%.

Sämsta landet var Österrike med en uppgång på 1,3%. Den bästa sektorn var palladium med en uppgång på 10,3%. Den sämsta sektorn var socker med en nedgång på 6,1%.  

De tre amerikanska ETF:erna med den bästa utvecklingen under veckan var*:

– First Trust Amex Biotechnology (Ticker FBT), 12,7%

– SPDR Metals & Mining (Ticker XME),  9,8%

– Market Vectors Steel (Ticker SLX), 8,9%

De tre amerikanska ETF:erna med den sämsta utvecklingen under veckan var*:

–   United States Natural Gas (Ticker UNG) , -4%

–  United States 12-Month Natural Gas (Ticker UNL), -3,8%

–  Vanguard Extended Duration Treasury (Ticker EDV), -3%